{"id":23,"date":"2010-11-11T13:00:45","date_gmt":"2010-11-11T04:00:45","guid":{"rendered":"https:\/\/labs.eng.hokudai.ac.jp\/labo\/labo_sample01\/?page_id=5"},"modified":"2020-06-30T22:27:41","modified_gmt":"2020-06-30T13:27:41","slug":"achievements","status":"publish","type":"page","link":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/achievements","title":{"rendered":"Publications"},"content":{"rendered":"<h1>Articles<\/h1>\n<h3>2020<\/h3>\n<ul>\n<li>Ag2O-catalysed nucleophilic isocyanation: selecive formation of less-stable benzyic isonitriles<br \/>\nT. Yurino, Y. Tange, R. Tani, T. Ohkuma<br \/>\n<em>Org. Chem. Front.<\/em> <strong>2020<\/strong> <em>accepted<\/em> (<a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2020\/qo\/d0qo00336k?fbclid=IwAR3CeLGQM9HHA2GQJ5rYETNBvj1zJG9Gs6k6WIZ2zDrWL_apqwpiXBylBHU#!divAbstract\">link<\/a>)<\/li>\n<li>Nucleophilic Isocyanation<br \/>\nT. Yurino, T. Ohkuma<br \/>\n<em>ACS Omega <\/em><strong>2020<\/strong><em>, 5,<\/em> <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.9b04073\">4719\u20134724. <\/a>(invited manuscript)<\/li>\n<li>Selective Conversion of Benzylic Phosphates into Diarylmethanes through Al(OTf)3-Catalyzed Friedel\u2013Crafts-type Benzylation<br \/>\nT. Yurino, A. Hachiya, K. Suzuki, T. Ohkuma<br \/>\n<em>Eur. J. Org. Chem.<\/em>\u00a0<strong>2020,<\/strong>\u00a0<em>2020<\/em>, <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/ejoc.202000077\">2225\u20132232<\/a><\/li>\n<li>T. Yurino, H. Ece, T. Ohkuma<br \/>\nFriedel\u2013Crafts-type Allylation of Phenol Derivatives Catalyzed by Silyl Cyanometallates Generated <em>In Situ<\/em><br \/>\n<em>Asian J. Org. Chem. <\/em><strong>2020<\/strong><em>,<\/em> <em>9<\/em>,\u00a0 <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/ajoc.202000023?fbclid=IwAR2C9RjM9nkQW5Meh5Ban9kgmA2D4_vWAgk6H1Cjd4qdxZZ5OlVMr5tLYuc\">557\u2013560.<\/a><\/li>\n<\/ul>\n<h3>2019<\/h3>\n<ul>\n<li>N. Arai, T. Ohkuma<br \/>\nStereoselective Preparation of Methylenecyclobutane-fused Angular Tetracyclic Spiroindolines via Photosensitized Intramolecular [2+2] Cycloaddition with Allene<br \/>\n<em>Tetrahedron Lett.\u00a0<\/em><strong>2019<\/strong>,\u00a0<em>60<\/em>, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0040403919310329\">151252\u2013151255.<\/a><\/li>\n<li>N. Arai, Y. Okabe, T. Ohkuma<br \/>\nIsomerization-Asymmetric Hydrogenation Sequence Converting Racemic \u03b2-Ylidenecycloalkanols into Stereocontrolled \u03b2-Substituted Cucloalkanols Using a Ru Catalytic System with Dual Roles<br \/>\n<em>Adv. Synth. Catal. <\/em><strong>2019,<\/strong><em> 361, <\/em><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adsc.201901269\">5540-5547.<\/a><\/li>\n<li>\n<div><span style=\"font-family: Helvetica;\">\u5927\u718a\u6bc5\u00a0 \u00a0\u00a0<\/span><\/div>\n<div><span style=\"font-family: Helvetica;\">\u30eb\u30c6\u30cb\u30a6\u30e0\u932f\u4f53\u89e6\u5a92\u3092\u7528\u3044\u308b\u30a4\u30df\u30f3\u985e\u306e\u4e0d\u6589\u6c34\u7d20\u5316\u53cd\u5fdc\u00a0<\/span><\/div>\n<div><span style=\"font-family: Helvetica;\">\u89e6\u5a92 <strong>2019<\/strong>, <i><span lang=\"EN-US\">61<\/span><\/i><span lang=\"EN-US\">, 291\u2013297<\/span><\/span><\/div>\n<\/li>\n<li>T. Yurino, R. Tani, T. Ohkuma<br \/>\nPd-Catalyzed Allylic Isocyanation: Nucleophilic\u00a0<em>N<\/em>-Terminus Substitution of Ambident Cyanide<br \/>\n<em>ACS Catal.\u00a0<\/em><strong>2019<\/strong>,\u00a0<em>9<\/em>, <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acscatal.9b00858\">4434\u20134440.<\/a><\/li>\n<li>N. Arai, T. Ohkuma<br \/>\nStereoselective Construction of Methylenecyclobutane-Fused Indolines through Photosensitized [2+2] Cycloaddition of Allene-Tethered Indole Derivatives<br \/>\n<em>Org. Lett.\u00a0<\/em><strong>2019<\/strong>,\u00a0<em>21<\/em>, <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.orglett.9b00309\">1506\u20131510.<\/a><\/li>\n<li>\u5927\u718a\u6bc5<br \/>\n\u300c\u30b8\u30e5\u30c3\u3068\u97f3\u304c\u3059\u308b\u89e6\u5a92\u3092\u4f5c\u308a\u305f\u3044\u3000\u9ad8\u6d3b\u6027\u4e0d\u6589\u6c34\u7d20\u5316\u89e6\u5a92\u958b\u767a\u596e\u95d8\u8a18\u300d<br \/>\n\u5316\u5b66\u3068\u5de5\u696d <strong>2019<\/strong>,\u00a0<em>72\u20133<\/em>, 259\u2013261.<\/li>\n<li>T. Ohkuma, N. Kurono, N. Arai<br \/>\nDevelopment of Asymmetric Reactions Catalyzed by Ruthenium Complexes with Two Kinds of Ligands (Award Accounts)<br \/>\n<em>Bull. Chem. Soc. Jpn.\u00a0<\/em><strong>2019,\u00a0<\/strong><em>92<\/em><strong>,<\/strong>\u00a0<a href=\"https:\/\/www.journal.csj.jp\/doi\/abs\/10.1246\/bcsj.20180328\">475\u2013504.<\/a><br \/>\n<img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1783 alignnone\" src=\"https:\/\/labs.eng.hokudai.ac.jp\/labo\/orgsynth\/wp-content\/uploads\/2019\/05\/BCSJ92-03-backcover.jpg\" alt=\"\" width=\"185\" height=\"249\" \/><br \/>\n*Advertised in Twitter of CSJ\uff08<a href=\"https:\/\/twitter.com\/CSJjournals_jp\/status\/1134263224130363392\">tweet 1<\/a>, <a href=\"https:\/\/twitter.com\/CSJjournals\/status\/1134263222582861824\">tweet 2<\/a>\uff09<\/li>\n<\/ul>\n<h3>2018<\/h3>\n<ul>\n<li>N. Utsumi, N. Arai, K. Kawaguchi, T. Katayama, T. Yasuda, K. Murata, T. Ohkuma*<br \/>\nAsymmetric Hydrogenation of Polysubstituted Aromatic Ketones Catalyzed by the DIPSkewphos\/PICA Derivative-Ruthenium(II) Complexes<br \/>\n<em>ChemCatChem<\/em>,\u00a0<strong>2018<\/strong>,\u00a0<em>10<\/em>,\u00a0<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/cctc.201800848\">3955\u20133959<\/a><\/li>\n<li>N. Arai, T. Ohkuma<br \/>\nConstruction of Unique Heterocyclic Frameworks by Photochemical Reaction of 5- and 6-Membered Heteroaromatics<br \/>\n<em>Heterocycles<\/em>,\u00a0<strong>2018<\/strong>,\u00a0<em>96<\/em>,\u00a0\u00a0<a href=\"https:\/\/www.heterocycles.jp\/newlibrary\/downloads\/PDF\/25149\/96\/6\">997\u20131035<\/a><br \/>\n(invited review)<\/li>\n<li>T. Ohkuma, N. Kurono, Y. Sakaguchi, K. Yamauchi, T. Yurino<br \/>\nEnantioselective Cyanosilylation of Alkynyl Ketones Catalyzed by Combined Systems Consisting of Chiral Rughtnium(II) Complex and Lithium Phenoxide<br \/>\n<em>Adv. Synth. Catal.\u00a0<\/em><strong>2018<\/strong>,\u00a0<em>360<\/em>,\u00a0<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adsc.201701593\/full\">1517\u20131522<\/a><\/li>\n<li>N. Arai, T. Namba, K. Kawaguchi, Y. Matsumoto and T. Ohkuma<br \/>\nChemoselectivitiy Control in the Asymmetric Hydrogenation of \u03b3- and \u03b4-Keto Esters into the Hydroxy Esters or the Diols<br \/>\n<em>Angew. Chem. Int. Ed.\u00a0<\/em><strong>2018<\/strong>,\u00a0<em>57<\/em>, <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201711363\/full\">1386\u20131389<\/a><\/li>\n<\/ul>\n<h3>2017<\/h3>\n<ul>\n<li>\u5927\u718a\u6bc5<br \/>\n\u3014\u7279\u96c6\u3015\u30ce\u30fc\u30d9\u30eb\u8cde\u53d7\u8cde\u6280\u8853\u30fb\u7406\u8ad6\u306e\u666e\u53ca\u3068\u5316\u5b66\u5de5\u696d\u306e\u5f79\u5272\u3000\u300c\u30ad\u30e9\u30eb\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\uff1a\u4e0d\u6589\u6c34\u7d20\u5316\u53cd\u5fdc\u300d<br \/>\n\u5316\u5b66\u5de5\u5b66 <em>81<\/em>(12), 666\u2013669 (2017)<\/li>\n<li>\u65b0\u4e95\u5247\u7fa9\u3001\u5927\u718a\u6bc5<br \/>\n\u3042\u306e\u8eab\u8fd1\u306a\u5316\u5408\u7269\u306f\u3053\u3046\u3084\u3063\u3066\u3064\u304f\u3089\u308c\u305f<br \/>\n\u73fe\u4ee3\u79d1\u5b66\u30002017\u5e7412\u6708\u53f7 18-23<\/li>\n<li>\u65b0\u4e95\u5247\u7fa9\u3001\u5927\u718a\u6bc5<br \/>\n\u6709\u6a5f\u5316\u5408\u7269\u306e\u3064\u304f\u308a\u304b\u305f\u4e8b\u59cb\u3081<br \/>\n\u73fe\u4ee3\u5316\u5b66\u30002017\u5e7411\u6708\u53f7 17\u201321<\/li>\n<li>N. Arai, T. Ohkuma<br \/>\nPhotochemically Promoted Aza-Diels-Alder-Type Reaction: High Catalytic Activity of the Cr(III)\/Bipyridine Complex Enhanced by Visible Light Irradiation<br \/>\n<em>J. Org. Chem. <\/em><strong>2017,<\/strong><strong>\u00a0<\/strong><em>82<\/em>,\u00a0<a href=\"http:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.7b00838\">7628\u20137636<\/a><\/li>\n<li>N. Arai, H. Satoh, R. Komatsu, T. Ohkuma<br \/>\nDouble Asymmetric Hydrogenation of Linea \u03b2,\u03b2-Disubstituted \u03b1,\u03b2-Unsaturated Ketones into \u03b3-Substituted Secondary Alcohols using a Dual Catalytic System<br \/>\n<em>Chem. Eur. J.\u00a0<\/em><strong>2017<\/strong>,\u00a0<em>23<\/em>, <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/chem.201701527\/full\">8806\u20138809<\/a>\u00a0(<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/chem.201701744\/epdf\">inside cover picture<\/a>)<\/li>\n<li>\u767e\u5408\u91ce\u5927\u96c5<br \/>\n\u6c34\u304b\u3089\u6c34\u7d20\u3092\u53d6\u308a\u51fa\u3057\u3066&#8221;\u79fb\u3057\u66ff\u3048\u308b&#8221;<br \/>\n\u6708\u520a\u5316\u5b66 2017\u5e742\u6708\u53f7<\/li>\n<li>T.\u00a0Yurino<br \/>\nUndirected Dehydrogenative Silylation of Aromatic C-H Bond<br \/>\n<em>J. Org. Synth. Chem. Jpn.\u00a0<\/em><strong>2017<\/strong>,\u00a0<em>75<\/em>, 64-65<\/li>\n<\/ul>\n<h3>2016<\/h3>\n<ul>\n<li>T. Ohkuma, N. Arai<br \/>\nAdvancement in Catalytic Asymmetric Hydrogenation of Ketones and Imines, and Development of Asymmetric Isomerization of Allylic Alcohols<br \/>\n<em>Chem. Rec.\u00a0<\/em><strong>2016<\/strong>,\u00a0<em>16<\/em>, 2797\u20132815 (Invited Paper)<\/li>\n<li>N. Arai, N. Onodera, T. Ohkuma<br \/>\nEfficient chemoselective hydrogenation of organic azides catalyzed by palladium nanoparticles with alkyne-derived homogeneous supports<br \/>\n<em>Tetrahedron Lett.\u00a0<\/em><strong>2016<\/strong>,\u00a0<em>57<\/em>, 4183\u20144186<\/li>\n<li>\u65b0\u4e95\u5247\u7fa9, \u5927\u718a\u3000\u6bc5<br \/>\n\u5149\u306b\u3088\u308b\u5206\u5b50\u6d3b\u6027\u5316\u3092\u5229\u7528\u3057\u305f\u542b\u30d8\u30c6\u30ed\u591a\u74b0\u7cfb\u9aa8\u683c\u69cb\u7bc9\u624b\u6cd5\u306e\u958b\u767a<br \/>\n\u6709\u6a5f\u5408\u6210\u5316\u5b66\u5354\u4f1a\u8a8c\u3000<strong>2016<\/strong>, <em>74<\/em>, 360\u2013371<\/li>\n<li>N. Kurono and T. Ohkuma,<br \/>\nCatalytic Asymmertic Cyanation Reactions.<br \/>\n<em>ACS Catalysis<\/em>, <strong>2016<\/strong>, <em>6<\/em>, 989\u20131023.<br \/>\n(Invited Review)<\/li>\n<\/ul>\n<h3>2015<\/h3>\n<ul>\n<li>\u65b0\u4e95\u5247\u7fa9, \u5927\u718a\u3000\u6bc5<br \/>\n25.1.4 \u6c34\u7d20\u30ac\u30b9\u3092\u7528\u3044\u308b\u9084\u5143\u6cd5\u2015\u89e6\u5a92\u306e\u8abf\u88fd\u3068\u53cd\u5fdc\u4f8b<br \/>\n\u6709\u6a5f\u5408\u6210\u5b9f\u9a13\u6cd5\u30cf\u30f3\u30c9\u30d6\u30c3\u30af\u3000\u7b2c\uff12\u7248 (\u6709\u6a5f\u5408\u6210\u5316\u5b66\u5354\u4f1a\u7de8)pp 852\u2013859 (\u4e38\u5584) (2015)<\/li>\n<li>N. Arai, N. Onodera, A. Dekita, J. Hori, and T. Ohkuma,<br \/>\nHydrogenation of Nitroarenes with Palladium Nanoparticles Stabilized by Alkyne Derivatives in Homogeneous Phase.<br \/>\n<em>Tetrahedron Letters<\/em>, <strong>2015<\/strong>, <em>56<\/em>, 3913\u20133915.<\/li>\n<li>N. Arai, M. Mizota, and T. Ohkuma,<br \/>\nStereoselective Preparation of Spiro[4.4] Cyclic Compounds by the Photochemical Activation of Oxazoles.<br \/>\n<em>Organic Letters<\/em>, <strong>2015<\/strong>, <em>17<\/em>, 86\u201389.<\/li>\n<li>N. Arai, M. Mizota, and T. Ohkuma,<br \/>\nNovel Intramolecular Cyclization-Skeletal Reorganization of 2-Arylthiazoles under Photoirradiation.<br \/>\n<em>Heterocycles<\/em>, <strong>2015<\/strong>, <em>90<\/em>, 607\u2013616.<br \/>\n(Isao Kuwajima\u2019s Special Issues)<\/li>\n<\/ul>\n<h3>2014<\/h3>\n<ul>\n<li>T. Ohkuma and N. Arai,<br \/>\n\u201cPhosphine, 1,1\u2019-(1<em>R<\/em>)-[1,1\u2019-binaphthalene]-2,2\u2019-diylbis[bis(4-methylphenyl)-<sup>1<\/sup> Phosphine, 1,1\u2019-(1<em>S<\/em>)-[1,1\u2019-binaphthalene]-2,2\u2019-diylbis[bis(4-methylphenyl)-<sup>1<\/sup>\u201d in <em>e-EROS Encyclopedia of Reagents for Organic Synthesis<\/em>, D. Crich, P. L. Fuchs, A. B. Charette, T. Rovis, Eds.; Wiley, 2014, pp 1-8.<\/li>\n<li>Y. Sakaguchi, N. Kurono, K. Yamauchi, and T. Ohkuma,<br \/>\nAsymmetric Conjugate Hydrocyanation of \u03b1,\u03b2-Unsaturated <em>N<\/em>-Acylpyrroles with the Ru(phgly)<sub>2<\/sub>(binap)\u2013CH<sub>3<\/sub>OLi Catalyst System.<br \/>\n<em>Organic Letters<\/em>, <strong>2014<\/strong>, <em>16<\/em>, 808\u2013811.<br \/>\n(<em>SYNFACTS 510 (<strong>2014<\/strong>)<\/em>)<\/li>\n<\/ul>\n<h3>2013<\/h3>\n<ul>\n<li>N. Arai, Y. Saruwatari, K. Isobe, and T. Ohkuma,<br \/>\nAsymmetric Hydrogenation of Quinoxalines, Benzoxazines, and a Benzothiazine Catalyzed by Chiral Ruthenabicyclic Complexes.<br \/>\n<em>Advanced Synthesis &amp; Catalysis<\/em>, <strong>2013<\/strong>, <em>355<\/em>, 2769\u20132774.<\/li>\n<li>N. Arai, K. Sato, K. Azuma, and T. Ohkuma,<br \/>\nEnantioselective Isomerization of Primary Allylic Alcohols into Chiral Aldehyde with the tol-binap\/dbapen\/Ruthenium(II) Catalyst.<br \/>\n<em>Angewandte Chemie, International Edition<\/em>, <strong>2013<\/strong>, <em>52<\/em>, 7500\u20137504.<br \/>\n(Selected as a Very Important Paper (VIP))<br \/>\n(Highlighted at the Inside Cover)<br \/>\n(<em>SYNFACTS 1092 (<strong>2013<\/strong>)<\/em>)<br \/>\n<img decoding=\"async\" loading=\"lazy\" class=\"wp-image-202 size-medium alignnone\" style=\"border: 1px solid #999;\" src=\"https:\/\/labs.eng.hokudai.ac.jp\/labo\/orgsynth\/wp-content\/uploads\/2016\/01\/Isomerization-Inside-Cover-AGC-212x300.jpg\" alt=\"Isomerization-Inside Cover-AGC\" width=\"212\" height=\"300\" \/><\/li>\n<li>N. Arai, H. Satoh, N. Utsumi, K. Murata, K. Tsutsumi, and T. Ohkuma,<br \/>\nAsymmetric Hydrogenation of Alkynyl Ketones with \u03b7<sup>6<\/sup>-Arene\/TsDPEN\u2013Ruthenium(II) Catalyst.<br \/>\n<em>Organic Letters<\/em>, <strong>2013<\/strong>, <em>15<\/em>, 3030\u20133033.<\/li>\n<li>N. Kurono, T. Katayama, and T. Ohkuma,<br \/>\nPreparation of Diastereomerically Pure and Mixed (<em>S<\/em>)-PhGly\/BIPHEP\/Ru(II) Complexes and Their Catalytic Behavior with Li<sub>2<\/sub>CO<sub>3<\/sub> in Asymmetric Cyanosilylation of Benzaldehyde.<br \/>\n<em>Bulletin of the Chemical Society of Japan<\/em>, <strong>2013<\/strong>, <em>86<\/em>, 577\u2013582.<br \/>\n(Selected Papers)<\/li>\n<\/ul>\n<h3>2012<\/h3>\n<ul>\n<li>N. Arai, N. Utsumi, Y. Matsumoto, K. Murata, K. Tsutsumi, and T. Ohkuma,<br \/>\nAsymmetric Hydrogenation of <em>N<\/em>-Arylimines Catalyzed by<br \/>\n<em>Advanced Synthesis &amp; Catalysis<\/em>, <strong>2012<\/strong>, <em>354<\/em>, 2089-2095.<br \/>\n(<em>SYNFACTS 1229 (<strong>2012<\/strong>)<\/em>)<\/li>\n<li>T.Ohkuma and N. Kurono<br \/>\nAsymmetric Cyanation with the Chiral Ru-Li Combined Catalysts.<br \/>\n<em>Synlett<\/em>, <strong>2012<\/strong>, <em>23<\/em>, 1865-1881. (Invited Account Paper)<\/li>\n<li>M. Uemura, N. Kurono, Y. Sakai, and T. Ohkuma,<br \/>\nEnantioselective Cyanosilylation of Ketones with\u00a0Amino Acids\/BINAP\/Ruthenium(II)-Lithium Phenoxide Catalyst Systems.<br \/>\n<em>Advanced Synthesis &amp; Catalysis<\/em>, <strong>2012<\/strong>, <em>354<\/em>, 2023-2030.<\/li>\n<li>N. Arai, K. Tanaka, and T. Ohkuma,<br \/>\nNovel Intramolecular Photocyclization of \u03b1-Arylthiophene Derivatives.<br \/>\n<em>Organic Letters.<\/em>, <strong>2012<\/strong>, <em>14<\/em>, 1488-1491.<\/li>\n<li>M. Uemura, N. Kurono, and T. Ohkuma,<br \/>\nEnantioselective Hydrocyanation of <em>N<\/em>-Protected Aldmines.<br \/>\n<em>Organic Letters<\/em>, <strong>2012<\/strong>, <em>14<\/em>, 882-885.<br \/>\n(<em>SYNFACTS 525 (<strong>2012<\/strong>)<\/em>)<\/li>\n<\/ul>\n<h3>2011<\/h3>\n<ul>\n<li>N. Kurono, K. Ohtsuga, M. wakabayashi, T. Kondo, H. Ooka, and T. Ohkuma,<br \/>\nKinetic Resolution of Racemic\u00a0<em>\u03b1-tert<\/em>-Alkyl-\u03b1-hydroxy Esters by Enantiomer-Selective\u00a0Carbamoylation.<br \/>\n<em>The Journal of Organic Chemistry<\/em>, <strong>2011<\/strong>, <em>76<\/em>, 10312-10318.<\/li>\n<li>M. Akashi, N. Arai, T. Inoue, and T. Ohkuma,<br \/>\nCatalyst-Controlled Diastereoselection in the Hydrogenation of Heterocycloalkyl Ketones.<br \/>\n<em>Advanced Synthesis &amp; Catalysis<\/em>, <strong>2011<\/strong>, <em>353<\/em>, 1955-1960.<br \/>\n(<em>SYNFACTS 1336 (<strong>2011<\/strong>)<\/em>)<\/li>\n<li>K. Matsumura, N. Arai, K. Hori, T. Sito, N. Sayo, and T. Ohkuma,<br \/>\nchiral Ruthenabicyclic Complexes: Precatalysts for Rapid, Enantioselective, and Wide-Scope\u00a0Hydrogenation of Ketones.<br \/>\n<i>Journal of the American Chemical Society<\/i>, <strong>2011<\/strong>, <em>133<\/em>, 10696-10699.<br \/>\n(SYNFACTS 968(2011))<\/li>\n<li>Kuroo. N.; Nii, N.; Sakaguchi, Y.; Uemura, M.; T.; Ohkuma, T.,<br \/>\nAsymmetric Hydrocyanation of <em>\u03b1,\u03b2<\/em>-Unsaturated Ketones into <em>\u03b2<\/em>-Cyano Ketones with<br \/>\nthe [Ru(phgly)<sub>2<\/sub>(binap)]\/C<sub>6<\/sub>H<sub>5<\/sub>OLi Catalyst System.<br \/>\n<em>Angewandte Chemie, International Edition<\/em>, <strong>2011<\/strong>, <em>50<\/em> (<em>24<\/em>), 5541-5544.<br \/>\n(<em>SYNFACTS 866 (<strong>2011<\/strong>)<\/em>)<\/li>\n<li>Kurono. N.; Yoshikawa. T.; Yamasaki. M.; Ohkuma. T.,<br \/>\nEnantioselective Hydrocyanation of Aldehydes Catalyzed by [Li{Ru(phgly)<sub>2<\/sub>(binap)}]X(X=Cl,\u00a0Br).<br \/>\n<em>Organic Letters<\/em>, <strong>2011<\/strong>, 13 (5), 1254-1257.<\/li>\n<li>Arai. N.; Ohkuma. T.,<br \/>\nIntramolecular iminium ene reaction with Cu(I) catalysis: facile formation of 4-amino-3-methylenechromans from O-propargyl salicyladehydes and dialkylamines.<br \/>\n<em>Tetrahedron<\/em>, <strong>2011<\/strong>, <em>67<\/em> (9), 1617-1622.<\/li>\n<\/ul>\n<h3>2010<\/h3>\n<ul>\n<li>Utsumi. N.; Tsutsumi, K.; Watanabe, M.; Murata, K.: Arai, N.; Kurono, N.; Ohkuma, T.,<br \/>\nAsymmetric hydrogenation of armatic heterocyclic ketones catalyzed by the MsDPEN-Cp<sub>^Ir<\/sub>(III)<br \/>\ncomplex.<br \/>\n<em>Heterocycles<\/em>, <strong>2010<\/strong>, <em>80<\/em>(1), 141-147.<\/li>\n<li>Ohkuma, T.,<br \/>\nAsymmetric hydrogenation of ketones: tactics to achieve high reactivity, enanitioselectivity, and wide scope.<br \/>\n<em>Proceedings of the Japan Academy, Series B: Physical and Biological Sciences<\/em>, <strong>2010<\/strong>, <em>86<\/em>(3),\u00a0202-219.<\/li>\n<li>Kurono, N.; Uemura, M.: Ohkuma, T.,<br \/>\nAsymmetric Cyanosilylation of \u03b1-Keto Esters Catalyzed by the [Ru(phgly)<sub>2<\/sub>(binap)]-C<sub>6<\/sub>H<sub>5<\/sub>OLi<br \/>\nSystem.<br \/>\n<em>European Journal of Organic Chemistry<\/em>. <strong>2010<\/strong>, (8), 1455-1459.<\/li>\n<li>Arai, N.; tanaka, K.; Ohkuma, T.,<br \/>\nPhotosensitized intramolecular cyclization of furan and non-activated alkene: pathway switching\u00a0by the substituent on the furan ring.<br \/>\n<em>Tetrahedron Letters<\/em>, <strong>2010<\/strong>, <em>51<\/em> (9), 1273-1275.<\/li>\n<li>Arai, N.: Akashi, M.: Sugizaki, S.; Ooka, H.; Inoue, T.; Ohkuma, T.;<br \/>\nAsymmetric Hydrogenation of Bicyclic Ketones Catalyzed by BINAP\/IPHAN-Ru(II) Complex.<br \/>\n<em>Organic Letters<\/em>, <strong>2010<\/strong>, <em>12<\/em> (15), 3380-3383.<br \/>\n(<em>SYNFACTS 1262 (<strong>2010<\/strong>)<\/em>)<\/li>\n<\/ul>\n<h3>2009<\/h3>\n<ul>\n<li>Tsutsumi, K.; Katayama, T.; Utsumi, N;, Murata, K,; Arai, N.; Kurono, N.; Ohkuma, T.,<br \/>\nPractical Asymmetric Hydrogenation of 3-Quinuclidinone Catalyzed by the XylSkewphos\/PICA-Ruthenium(II) Complex.<br \/>\n<em>Organic Process Research &amp; Development<\/em>, <strong>2009<\/strong>, <em>13<\/em> (3), 625-628.<\/li>\n<li>Hori, J.; Murata, K.; Sugai, T.; Shinohara, H.; Noyori, R.; Arai, N.; Kurono, N.; Ohkuma, T.,<br \/>\nHighly Active and Selective Semihydrogenation of Alkynes with the Palladium Nanoparticles-Tetrabutylammonuium Borohydride Catalyst System.<br \/>\n<em>Advanced Synthesis &amp; Catalysis<\/em>, <strong>2009<\/strong>, <em>351<\/em> (18), 3143-3149.<\/li>\n<\/ul>\n<h3>2008<\/h3>\n<ul>\n<li>Ooka, H.; Arai, N.; Azuma, K.; Kurono, N.; Ohkuma, T.,<br \/>\nAsymmetric Hydrogenation of Aromatic Ketones Catalyzed by the TolBINAP\/DMAPEN-Ruthenium(II) Complex; A Significant Effect of N-Substituents of Chiral 1.2-Diamine Ligands on\u00a0Enantioselectivity.<br \/>\n<em>The Journal of Organic Chemistry<\/em>, <strong>2008<\/strong>, <em>73<\/em> (22), 9084-9093.<\/li>\n<li>Ohkuma, T.,<br \/>\nAsymmetric hydrogenation of ketones using tailor-made catalyst.<br \/>\n<em>Organometallic News<\/em>, <strong>2008<\/strong>, (1), 8-13.<\/li>\n<li>Kurono, N.; Kondo, T.; Wakabayahi, M.; Ooka, H.; Inoue, T.; Tachikawa, H.; Ohkuma, T.,<br \/>\nEnantiomer-selective carbamoylation of racemic \u03b1-hydroxy gamma-Lactones with chiral Cu(II)\u00a0Catalysts; an example of highly active Lewis acid catalyzed reaction.<br \/>\n<em>Chemistry, an Asian Journal<\/em>, <strong>2008<\/strong>, <em>3<\/em> (8-9), 1289-1297.<\/li>\n<li>Kurono, N.; Arai, K.; Uemura, M.; Ohkuma, T.,<br \/>\n[Ru(phgly)<sub>2<\/sub>(binap)]\/Li<sub>2<\/sub>CO<sub>3<\/sub>: a highly active, robust, and enantioselective catalyst for the\u00a0cyanosilylation of aldehydes.<br \/>\n<em>Angewandte Chemie, International Edition<\/em>, <strong>2008<\/strong>, <em>47<\/em> (35), 6643-6646.<br \/>\n(SYNFACTS 1192 (2008))<\/li>\n<li>Arai, N.; Suzuki, K.; Sugizaki, S.; Sorimachi, H.; Ohkuma, T.,<br \/>\nAsymmetric hydrogenation of aromatic, aliphatic, and alpha, beta-unsaturated acyl silanes\u00a0catalyzed by Tol-binap\/Pica ruthenium(II) complexes: practical synthesis of optically active\u00a0alpha-hydroxysilanes.<br \/>\n<em>Angewandte Chemie, International Edition<\/em>, <strong>2008<\/strong>, <em>47<\/em> (9), 1770-1773.<br \/>\n(<em>SYNFACTS 503 (<strong>2008<\/strong>)<\/em>)<\/li>\n<li>Arai, N.; Azuma, K.; nii, N.; Ohkuma, T.,<br \/>\nHighly enantioselective hydrogenation of arylvinyl ketones to allylic alcohols catalyzed by the\u00a0tol-binap\/dmapen ruthenium(II) complex.<br \/>\n<em>Angewandte Chemie, International Edition<\/em>, <strong>2008<\/strong>, <em>47<\/em> (39), 7457-7460.<\/li>\n<\/ul>\n<h3>2007<\/h3>\n<ul>\n<li>Ohkuma, T.; Utsumi, N.; Watanabe, M.; Tsutsumi, K,; Arai, N.; Murata, K.,<br \/>\nAsymmetric hydrogenation of alpha-hydroxy ketones catalyzed by MsDPEN-Cp<sub>^Ir<\/sub>(III) complex.<br \/>\n<em>Organic Letters<\/em>, <strong>2007<\/strong>, <em>9<\/em> (13), 2565-2567.<\/li>\n<li>Ohkuma, T.; Tsutsumi, K.; Utsumi, N.; Arai, N.; Noyori, R.; Murata, K.,<br \/>\nAsymmetric hydrogenation of alpha-chloro aromatic ketones catalyzed by \u03b7<sup>6<\/sup>-arene\/TsDPEN-ruthenium(II) complexes.<br \/>\n<em>Organic Letters<\/em>, <strong>2007<\/strong>, <em>9<\/em> (2), 255-257.<\/li>\n<li>Ohkuma, T.,<br \/>\nTailor-made catalysts for asymmetric hydrogenation of ketones.<br \/>\n<em>Yuki Gosei Kagaku Kyokaishi<\/em>, <strong>2007<\/strong>, <em>65<\/em> (11), 1070-1080.<\/li>\n<li>Arai, N.; Ooka, H.; Azuma, K.; Yabuuchi, T.; Kurono, N.; Inoue, T.; Ohkuma, T.,<br \/>\nGeneral asymmetric hydrogenation of alpha-branched aromatic ketones catalyzed by\u00a0TolBINAP\/DMAPEN-ruthenium(II) complex.<br \/>\n<em>Organic Letters<\/em>, <strong>2007<\/strong>, <em>9<\/em> (5), 939-941.<\/li>\n<\/ul>\n<h3>2006<\/h3>\n<ul>\n<li>Ohkuma, T.; Utsumi, N.; Tsutsumi, K.; Murata, K.; Sandoval, C.; Noyori, R.,<br \/>\nThe Hydrogenation\/Transfer Hydrogenation Network: Asymmetric Hydrogenation of Ketones\u00a0with Chiral \u03b7<sup>6<\/sup>-Arene\/N-Tosylethylenediamine-Ruthenium(II) Catalysts.<br \/>\n<em>Journal of the American Chemical Society<\/em>, <strong>2006<\/strong>, <em>128<\/em> (27), 8724-8725.<\/li>\n<li>Kurono, N.; Suzuki, K.; Ohkuma, T.,<br \/>\nCyanosilylation of hetero-substituted ketones catalyzed by LiCl.<br \/>\n<em>Letters in Organic Chemistry<\/em>, <strong>2006<\/strong>, <em>3<\/em> (4), 275-277.<\/li>\n<\/ul>\n<h1>Reviews (Monographs)<\/h1>\n<ul>\n<li>T. Yurino, T. Ohkuma<br \/>\n<a href=\"https:\/\/www.worldscientific.com\/worldscibooks\/10.1142\/q0192\"><em>Atropisomerism and Axial Chirality,<\/em><\/a> Lassaletta, J. M. Ed.; World Scientific<br \/>\nSingapore, 2019, pp 149\u2013247.<\/li>\n<li>\u5927\u718a\u3000\u6bc5,<br \/>\n\u30b1\u30c8\u30f3\u985e\u304a\u3088\u3073\u30a4\u30df\u30f3\u985e\u306e\u74b0\u5883\u8abf\u548c\u578b\u4e0d\u6589\u6c34\u7d20\u5316\u89e6\u5a92\u306e\u958b\u767a\u3068\u5fdc\u7528.<br \/>\n\u30d5\u30a1\u30eb\u30de\u30b7\u30a2, 2015, 51, 295\u2013299.<\/li>\n<li>N. Arai and T. Ohkuma,<br \/>\nDesign of Molecular Catalysis for Achievement of High Turnover Number in Homogeneous\u00a0Hydrogenation.<br \/>\n<em>Chem. Rec.<\/em>, 2012, 12, 284-289.<\/li>\n<li>Ohkuma, T.; Kurono, N.,<br \/>\n&#8220;BINAP&#8221; in <em>Privileged Chiral Ligands and Catalysts<\/em>, Zhou. Q.-L., Ed.; Wiley-VCH:<br \/>\nWeinheim, 2011, pp 1-53.<\/li>\n<li>Arai, N., Ohkuma, T.,<br \/>\n&#8220;Reduction of Carbonyl Compound: Hydrogenation&#8221; in Science of <em>Synthesis:<\/em><br \/>\n<em>Stereoselective Synthesis 2: Stereoselective Reactions of Carbonyl and lmino Groups,<\/em><br \/>\nMolander, G. A., Ed.: Thieme: Stuttgart, 2010, pp 9-57.<\/li>\n<li>Arai, N., Ohkuma, T.<br \/>\n&#8220;Carbonyl Hydroboration&#8221; in Modern Reduction Methods, Anderson, P., Munslow, I., Eds.;<br \/>\nWiley-VCH: Weinheim, 2008, pp 159-181.<\/li>\n<li>Ohkuma, T., Kitamura, M., Noyori, R.<br \/>\n&#8220;Ligand Design for Catalytic Asymmetric Reduction&#8221; in <em>New Frontiers in Asymmetric<\/em><br \/>\n<em>Catalysisi<\/em>, Mikami K., Lautens, M. Eds.; Wiley: New Jersey, 2007, pp 1-32.<\/li>\n<li>Ohkuma, T., Noyori, R.<br \/>\n&#8220;Enantioselective Ketone and \u03b2-Keto Ester Hydrogenation (Including Mechanisms)&#8221; in <em>The\u00a0Handbook of Homogeneous Hydrogenation<\/em>, de Vries, J. G., Elsevier, C. J., Eds.; Wiley-VCH: Weinheim, 2007: Vol.3 pp 1105-1163.<\/li>\n<\/ul>\n<h1>Press Release<\/h1>\n<ul>\n<li>\u5316\u5b66\u5de5\u696d\u65e5\u5831\u30002020\u5e746\u670811\u65e5\u3000\u8a18\u4e8b\u63b2\u8f09<br \/>\n\u300c\u4e0d\u6589\u6c34\u7d20\u5316\u89e6\u5a92\u3092\u65b0\u958b\u767a\u3000\u533b\u85ac\u54c1\u5411\u3051\u53d7\u8a17\u5408\u6210\u3082\u6d3b\u6cc1\u300d<\/li>\n<li>\u5317\u6d77\u9053\u65b0\u805e\u3000\u30002013\u5e7412\u670826\u65e5 \u8a18\u4e8b\u63b2\u8f09<br \/>\n\u300c\u307f\u3093\u306a\u3067\u30b5\u30a4\u30a8\u30f3\u30b9\u3000\u540c\u3058\u5206\u5b50\u306b\u7570\u306a\u308b\u6027\u8cea\uff1f\u3000\u4f5c\u308a\u5206\u3051\u306e\u6280\u8853\u3092\u958b\u767a\u300d<br \/>\n\uff08\u672c\u5b66\u79d1\u5b66\u6280\u8853\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u6559\u80b2\u7814\u7a76\u90e8\u9580CoSTEP\u3000\u5409\u7530\u3086\u304b\u308a\u3000\u7279\u4efb\u51c6\u6559\u6388\u3000\u57f7\u7b46\uff09<\/li>\n<li>\u65e5\u7d4c\u7523\u696d\u65b0\u805e\u30002013\u5e747\u670817\u65e5\u3000\u8a18\u4e8b\u63b2\u8f09<br \/>\n\u300c\u30a2\u30eb\u30c7\u30d2\u30c9\u3001\uff11\u56de\u3067\u5408\u6210\u3000\u3000\u5317\u6d77\u9053\u5927\u3000\u65b0\u89e6\u5a92\u3067\u7d14\u5ea699\uff05\u8d85\u300d<\/li>\n<li>\u5316\u5b66\u5de5\u696d\u65e5\u5831\u30002011\u5e746\u670829\u65e5\u3000\u8a18\u4e8b\u63b2\u8f09<br \/>\n\u300c\u8d85\u9ad8\u901f\u306e\u4e0d\u6589\u6c34\u7d20\u5316\u89e6\u5a92\u300d<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Articles 2020 Ag2O-catalysed nucleophilic isocyanation: selecive formation of less-stable benzyic isonitriles  [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/pages\/23"}],"collection":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/comments?post=23"}],"version-history":[{"count":4,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/pages\/23\/revisions"}],"predecessor-version":[{"id":970,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/pages\/23\/revisions\/970"}],"wp:attachment":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/orgsynth.eng\/en\/wp-json\/wp\/v2\/media?parent=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}